Borderlands has corrosion, which works like a poison.
Team Fortress 2 has a few weapons that inflict Bleeding, which deals damage over time much like Afterburn, but can only be stopped by picking up a Medkit. Additionally, if Olimar throws a white Pikmin at an opponent and hits them, they'll take constant damage until the Pikmin is knocked off. Melee and Brawl have a similar effect in which a flower attached to someone's head will cause constant damage. In Light Crusader, poison switches around controls instead of sapping health. Soma (the reincarnation of Dracula) and Alucard (A Dhampyr) Are immune to the damage, but still get lowered stats. So far, all the strictly human characters take gradual damage from poison. It seems to depend on the character poisoned. And in Castlevania: Order of Ecclesia, poison drains your health AND lower your stats. In Castlevania: Circle of the Moon, poison drains your health, but doesn't lower your stats. In Castlevania: Portrait of Ruin, not only does poison severely lower your stats, but it also drains your health. Reversed with the Zombie soul - when equipped, you actually get stronger while poisoned. In Castlevania: Aria of Sorrow, the Poison status reduces your stats and attack power considerably, but otherwise does no HP damage. This can sometimes get hilariously out of hand, as evidenced here. Some games ( Tales of Symphonia, Pokémon) have both regular poisons and stronger, more potent poisons that sap more health at a time. If the game in question doesn't automatically cure status effects at the end of each battle, this effect almost always lingers until cured, often draining a bit of HP even outside of battle with each step you take. In turn-based games, it will deal a set amount of damage at the beginning (sometimes end) of each turn. There's also the case of the One Curse Limit in which one status ailment can be overwritten by a second entirely separate status ailment Note that despite what is said below, any status effect that prevents a character from taking any action may sometimes disappear on any hit (especially if there are not other party members in this game), and many of them will often fix themselves after several rounds, even if they're permanent until cured in other games. Many of the status ailments have equivalent Status Buffs, with opposite effects. They can even appear in platformers and puzzle games. They might also appear in Real Time Strategy (to accentuate the "strategy" part), and occasionally in First Person Shooters and Third Person Shooters, mostly those with RPG Elements. Then again, anti-venom in Real Life is actually made from the venom itself so there may be some kernel of Truth in Television in that aspect. By some inexplicable homeopathy by design, monsters that cause these effects will frequently drop the item that cures it. Games with these effects will usually feature a spell or item that cures each one individually, as well as another item, encountered later, that will cure all of them. 
It may be that gamers are so hardwired to expect certain effects from certain conditions that trying to change them is more trouble than it's worth.Īs documented in Useless Useful Spells, these effects are almost always going to get used on you, thanks to the fact that they tend to linger and continue to hurt you outside of battle unlike you, enemies always show up for battle in full health. And the same status effects will show up in every game. Paralysis is going to keep you from moving. For some reason, the effects of hazardous status effects, within the rules of the game, almost never change.
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